This guide offers a collection of estimation methods selected from a range of sources that we believe may prove helpful in estimating musculoskeletal disorders (MSD) risk factors in machinery design. It does not claim to be a "quick-fix" problem solver for evaluating every risk factor. With this guide, we aim to feed knowledge from the actual use of machines back to designers' and manufacturers' drawing boards. We mean to factor the end users' perspectives into the design process by showing how workplace knowledge can be channelled into the conceptual of machinery design.